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Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Biochemistry

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

AND

Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Selected by 09 May 2019

Pavithran Ravindran

Bioengineering

A Bile Duct-on-a-Chip with Organ-Level Functions

Yu Du, Gauri Khandekar, Jessica Llewellyn, et al.

Selected by 19 April 2019

Zhang-He Goh

Bioengineering

ATAT1-enriched vesicles promote microtubule acetylation via axonal transport

Aviel Even, Giovanni Morelli, Chiara Scaramuzzino, et al.

Selected by 13 March 2019

Stephen Royle

Cell Biology

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Marion Regnier, Arnaud Polizzi, Sarra Smati, et al.

Selected by 07 March 2019

Pablo Ranea Robles

Pathology

MicroRNA-mediated control of developmental lymphangiogenesis

Hyun Min Jung, Ciara Hu, Alexandra M Fister, et al.

Selected by 07 March 2019

Rudra Nayan Das

Developmental Biology

Prospective, brain-wide labeling of neuronal subclasses with enhancer-driven AAVs

Lucas T Graybuck, Adriana Sedeño-Cortés, Thuc Nghi Nguyen, et al.

Selected by 27 February 2019

Jesus Victorino

Neuroscience

SorCS1-mediated Sorting of Neurexin in Dendrites Maintains Presynaptic Function

Luis Filipe Ribeiro, Ben Verpoort, Julie Nys, et al.

Selected by 27 February 2019

Carmen Adriaens

Cell Biology

Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability

Mark R Sullivan, Laura V Danai, Caroline A Lewis, et al.

Selected by 11 February 2019

Maria Rafaeva

Cancer Biology

EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake

Claudia Matthaeus, Ines Lahmann, Severine Kunz, et al.

Selected by 04 February 2019

Andreas Müller

Cell Biology

Large-scale analyses of human microbiomes reveal thousands of small, novel genes and their predicted functions

Hila Sberro, Nicholas Greenfield, Georgios Pavlopoulos, et al.

Selected by 23 January 2019

Ganesh Kadamur

Bioinformatics

LADL: Light-activated dynamic looping for endogenous gene expression control

Mayuri Rege, Ji Hun Kim, Jacqueline Valeri, et al.

Selected by 10 August 2018

Ivan Candido-Ferreira

Genomics
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